{"id":19842,"date":"2024-08-13T03:47:48","date_gmt":"2024-08-13T07:47:48","guid":{"rendered":"https:\/\/www.capilclinic.us\/?p=14385"},"modified":"2025-11-10T13:24:01","modified_gmt":"2025-11-10T21:24:01","slug":"genes-that-cause-alopecia","status":"publish","type":"post","link":"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/","title":{"rendered":"The 287 Genes That Cause Alopecia"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_85 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Contenidos<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/#What_is_hair_loss\" >What is hair loss?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/#A_General_Discussion_About_Baldness_and_the_genes_that_cause_alopecia\" >A General Discussion About Baldness and the genes that cause alopecia<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/#How_predictable_is_baldness_generated_by_the_genes_that_cause_alopecia\" >How predictable is baldness generated by the genes that cause alopecia?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/#What_Other_Factors_Besides_Genes_That_Cause_Alopecia_Contribute_to_Hair_Loss_and_Baldness\" >What Other Factors Besides Genes That Cause Alopecia Contribute to Hair Loss and Baldness?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/#The_Treatment_of_Baldness\" >The Treatment of Baldness<\/a><ul class='ez-toc-list-level-3' ><li class='ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/#Finasteride\" >Finasteride<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-3'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/www.capilclinic.us\/blog\/genes-that-cause-alopecia\/#Minoxidil\" >Minoxidil<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<p>It\u2019s not unusual for people to shed a few hairs from their scalp daily. If you notice that your hair is falling out more quickly than usual or that it is becoming thinner. you may be going bald. As we become older, the majority of us experience <strong>thinning hair.<\/strong> Most of the time, it has something to do with heredity and the normal aging process. In other instances, <strong>hair loss<\/strong> could result from a preexisting medical issue.There are some genes that cause <strong>alopecia<\/strong>. In this article we will talk about The 287 <strong>Genes That Cause Alopecia<\/strong>.<\/p>\n<p><strong>Baldness<\/strong> is an extremely prevalent ailment that affects almost half of all males by the time they reach the age of 50. Women can also be affected, though this is far less common. And the condition typically only manifests itself at the highest pinnacle of the head. Some individuals see baldness as a natural and unavoidable consequence of aging. It can be upsetting for other people. Several therapies are available for baldness; however, there is no known cure for the condition. In this article we will talk about the genes that cause alopecia.<\/p>\n<p>Maybe you are interested: <a class=\"tptn_link\" href=\"https:\/\/www.capilclinic.us\/risk-hair-transplant-rejection\/\"><span class=\"tptn_title\">Risk Of Hair Transplant Rejection<\/span><\/a><\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_is_hair_loss\"><\/span>What is hair loss?<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-7337\" src=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2019\/12\/avoid-hair-loss.jpg\" alt=\"avoid hair loss\" width=\"560\" height=\"335\" srcset=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2019\/12\/avoid-hair-loss.jpg 560w, https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2019\/12\/avoid-hair-loss-300x179.jpg 300w\" sizes=\"auto, (max-width: 560px) 100vw, 560px\" \/><\/p>\n<p><strong>Hair loss is a complex process that involves many factors.<\/strong> While genes play a major role, there are also other elements at play:<\/p>\n<ul>\n<li><strong>Hormones:<\/strong> Androgens like testosterone and DHT regulate hair growth cycles. Fluctuations or imbalances can trigger hair loss.<\/li>\n<li><strong>Age:<\/strong> As we get older, hair follicles may shrink and produce thinner hair strands.<\/li>\n<li><strong>Stress:<\/strong> High stress levels accelerate hair shedding and can lead to sudden hair loss.<\/li>\n<li><strong>Medical conditions:<\/strong> Thyroid disorders, lupus, iron deficiency can all cause excessive hair loss.<\/li>\n<li><strong>Medications:<\/strong> Certain drugs used to treat health issues like depression, heart disease, arthritis, etc. list hair loss as a side effect.<\/li>\n<li><strong>Environmental factors:<\/strong> air pollution, poor nutrition, smoking, and harsh hair products also contribute to thinning hair.<\/li>\n<\/ul>\n<p>So while genetic predisposition determines how sensitive your hair follicles are, other internal and external factors often act as triggers that set off the hair loss process.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"A_General_Discussion_About_Baldness_and_the_genes_that_cause_alopecia\"><\/span><strong>A General Discussion About Baldness and the genes that cause alopecia<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-19409\" src=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2022\/12\/Genes-That-Cause-Alopecia-4.jpg\" alt=\"Genes That Cause Alopecia\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2022\/12\/Genes-That-Cause-Alopecia-4.jpg 600w, https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2022\/12\/Genes-That-Cause-Alopecia-4-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>Loss of hair can begin at any point in one\u2019s life. The temples are the first areas to show signs of thinning hair in men. And over time, the hairline will gradually recede, creating an \u2018M\u2019 shape. At some point, certain guys will lose all of their hair<\/strong>. Hereditary male pattern baldness is connected to high levels of the hormone DHT. Which is produced when testosterone is converted into another hormone called dihydrotestosterone (DHT). DHT is responsible for the reduction in the size of hair follicles.<\/p>\n<p><strong>DHT causes hair loss by binding to receptors in hair follicles, triggering them to shrink.<\/strong> This progressively miniaturizes the follicles until they no longer produce visible hair strands. DHT also has a shortening effect on the hair\u2019s growth phase. As a result, new hairs grow back finer and thinner after each cycle until they don\u2019t grow back at all.<\/p>\n<p>When women experience female pattern baldness, their hair thins down everywhere and sometimes in patches on top of their heads. But their hairlines don\u2019t recede, and they rarely become completely bald. It is not believed that female pattern baldness is caused by a genetic predisposition. Because its causes are not as well understood. Male pattern baldness is more common after menopause.\u00a0 Researchers can infer that it may be related to changes in hormone levels.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-16063\" src=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia-2-e1720027117921.jpg\" alt=\"hair loss in men symptoms\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia-2-e1720027117921.jpg 600w, https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia-2-e1720027117921-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/p>\n<p>One of the most important aspects of male pattern baldness is the level of androgens, which are male hormones. The hairs become shorter and finer as the concentration of androgens in the body rises. Which may eventually prevent new hairs from growing to replace the ones that fall out. Other aspects, like genetics, also have a role.<\/p>\n<p>The main androgen responsible for hair loss is dihydrotestosterone (DHT). This is a derivative of testosterone that causes shrinkage and miniaturization of hair follicles. Genetics influence how sensitive your hair follicles are to DHT &#8211; some may be overly sensitive, while others remain unaffected.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"How_predictable_is_baldness_generated_by_the_genes_that_cause_alopecia\"><\/span><strong>How predictable is baldness generated by the genes that cause alopecia?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-20231\" src=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia.jpg\" alt=\"\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia.jpg 600w, https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>People affected by male pattern baldness are more likely to have relatives who also suffer from the condition. The likelihood of you having pattern baldness increases if you have a close relative who already suffers from the condition.<\/strong> It is widely believed and accepted in folklore that baldness is inherited from one\u2019s mother\u2019s family. It\u2019s not only one parent\u2019s genes that cause hair loss. These genes can be inherited from either parent\u2019s side of the family; they cause alopecia.<\/p>\n<p>If one or both of your parents experienced hair loss, you have a higher chance of developing it too. However, the exact genes responsible are still being researched. So far, over 280 gene variants have been associated with male and female pattern baldness. These genetic markers can predict your risk, but external factors also play a role. Lifestyle, hormones, and age &#8211; all affect how and when these genes get \u201cswitched on.\u201d<\/p>\n<p><strong>The research discovered 287 genetic variants or genes that cause alopecia in a study conducted in 2017 and published in PLOS Genetics.<\/strong> Their in-depth genetic research can estimate the likelihood of a person acquiring male pattern hair loss.\u00a0 But the results are only partially accurate.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"What_Other_Factors_Besides_Genes_That_Cause_Alopecia_Contribute_to_Hair_Loss_and_Baldness\"><\/span><strong>What Other Factors Besides Genes That Cause Alopecia Contribute to Hair Loss and Baldness?<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Even though the hair loss gene plays a significant part in hereditary hair loss, other factors can still contribute to baldness. When a woman reaches menopause, it is not uncommon for her to begin experiencing hair loss. On the other hand, men typically begin to suffer from balding in their young adulthood. The following are some more factors that may contribute to hair loss:<\/p>\n<ul>\n<li>Changes in hormone levels<\/li>\n<li>Alopecia areata<\/li>\n<li>Styles of hair that are stressful to maintain, such as tight ponytails<\/li>\n<li>Nutritional deficiencies<\/li>\n<li>Medicines and dietary supplements<\/li>\n<li>Stress<\/li>\n<li>Birth control<\/li>\n<li>Trichotillomania<\/li>\n<li>Therapy with radiation<\/li>\n<\/ul>\n<p>While genetics load the gun, lifestyle and environmental factors pull the trigger when it comes to hair loss. Factors that can accelerate genetic hair loss include:<\/p>\n<ul>\n<li>Stress &#8211; Causes inflammation and hormonal changes<\/li>\n<li>Smoking &#8211; Impairs blood flow to the scalp<\/li>\n<li>Nutrient deficiencies &#8211; Lack of proteins, iron, and zinc stunts hair growth<\/li>\n<li>Harsh hair care &#8211; Heat styling and tight hairstyles damage follicles<\/li>\n<li>Hormonal changes &#8211; Puberty, pregnancy, and menopause alters androgen levels<\/li>\n<li>Chronic diseases &#8211; diabetes and lupus leads to hair shedding<\/li>\n<li>Medications &#8211; Blood thinners, antidepressants, and chemotherapy drugs<\/li>\n<li>Pollution &#8211; Toxins weaken hair proteins, causing breakage<\/li>\n<\/ul>\n<p>So while you can\u2019t change your genetics, you can modify these external factors to some extent. Controlling stress levels, eating a nutrient-rich diet, using gentle hair products, and quitting smoking \u2212 all help reduce hair fall.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"The_Treatment_of_Baldness\"><\/span><strong>The Treatment of Baldness<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-full wp-image-16062\" src=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia-3.jpg\" alt=\"bald man with one hand on his head looking at the camera with a faint smile\" width=\"600\" height=\"400\" srcset=\"https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia-3.jpg 600w, https:\/\/www.capilclinic.us\/blog\/wp-content\/uploads\/2023\/01\/The-287-Genes-That-Cause-Alopecia-3-300x200.jpg 300w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><\/p>\n<p><strong>When women experience female pattern baldness, their hair thins down everywhere and sometimes balds in patches on top of their heads, but their hairlines don\u2019t recede, and they rarely become completely bald<\/strong>. It is not believed that female pattern baldness is caused by a genetic predisposition because its causes are not as well understood. It has been hypothesized that fluctuating hormone levels play a role in the increased frequency of baldness following menopause.<\/p>\n<p>Treatments for genetic hair loss aim to slow or stop the effects of DHT on hair follicles. The two FDA approved medical treatments are:<\/p>\n<ol>\n<li><strong>Finasteride<\/strong> &#8211; Stops the conversion of testosterone to DHT<\/li>\n<li><strong>Minoxidil<\/strong> &#8211; Improves blood flow and nutrients to follicles<\/li>\n<\/ol>\n<p>These drugs help retain existing hair and regrow new strands. They work better at catching hair loss early than reversing advanced balding. Results can take 3-6 months, and effects reverse once you stop medications.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Finasteride\"><\/span><strong>Finasteride<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>Finasteride is a medication for male pattern hair loss that comes in the form of a tablet and should be taken once daily.\u00a0 This medicine is effective in reducing hair loss and even stimulating new hair growth by inhibiting the generation of the hormone that causes it.<\/strong> The conversion of testosterone into dihydrotestosterone is prevented. Which is the key to its efficacy. DHT is responsible for reducing the size of hair follicles, which is the underlying cause of hair loss.<\/p>\n<h3><span class=\"ez-toc-section\" id=\"Minoxidil\"><\/span><strong>Minoxidil<\/strong><span class=\"ez-toc-section-end\"><\/span><\/h3>\n<p><strong>You can treat both male and female pattern baldness with minoxidil. It is available over the counter and comes in the form of a lotion that you can massage once a day into your scalp. It is not known how it operates, but studies have shown that it can prevent or halt the progression of hair thinning and stimulate new hair growth in others.<\/strong> Minoxidil is more effective for women than men; only about 1 in 4 women report seeing their hair return after using it.<\/p>\n<p>When using minoxidil, you won\u2019t start to see any results for at least a few months, much like with finasteride. If you discontinue using it, whatever new hair has grown will fall out, and the balding cycle will restart as normal. There is a 2% strength, as well as a 5% strength, available. Although it is unclear whether the lotion with 5% is more efficient, it is more likely to induce side effects like a dry and itchy scalp. This is because it contains a higher concentration of the active substance.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>It\u2019s not unusual for people to shed a few hairs from their scalp daily. If you notice that your hair is falling out more quickly&hellip; <\/p>\n","protected":false},"author":1,"featured_media":19408,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11],"tags":[],"class_list":["post-19842","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-hair-loss-alopecia"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>The 287 Genes That Cause Alopecia - Capilclinic USA Blog<\/title>\n<meta name=\"description\" content=\"In this article we will introduce you The 287 Genes That Cause Alopecia. 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